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DeCS
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Descriptor English:
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GRB2 Adaptor Protein
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Descriptor Spanish:
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Proteína Adaptadora GRB2
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Descriptor Portuguese:
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Proteína Adaptadora GRB2
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Synonyms English:
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Abundant Src Homology Protein
GRB2 Adaptor Protein, Grb3 3 Isoform
GRB2 Adaptor Protein, Grb3-3 Isoform
Grb3-3 Adaptor Protein
Growth Factor Receptor Bound Protein 2
Growth Factor Receptor-Bound Protein-2
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Tree Number:
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D12.644.360.024.290
D12.776.157.057.041
D12.776.476.024.377
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Definition English:
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A signal transducing adaptor protein that links extracellular signals to the MAP KINASE SIGNALING SYSTEM. Grb2 associates with activated EPIDERMAL GROWTH FACTOR RECEPTOR and PLATELET-DERIVED GROWTH FACTOR RECEPTORS via its SH2 DOMAIN. It also binds to and translocates the SON OF SEVENLESS PROTEINS through its SH3 DOMAINS to activate PROTO-ONCOGENE PROTEIN P21(RAS). |
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History Note English:
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2006(1992)
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Allowable Qualifiers English:
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Record Number:
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50766
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Unique Identifier:
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D051380
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Occurrence in VHL:
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Similar:
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DeCS
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